The word " portal " refers to the hepatic portal circulation from the digestive system to the liver.
2.
Along the proximal and distal ileum, these conjugated primary bile salts are reabsorbed actively into hepatic portal circulation.
3.
Bacteria deconjugate some of the primary and secondary conjugated bile salts back to lipid-soluble bile acids, which are passively absorbed into hepatic portal circulation.
4.
In order for drugs to be absorbed, they must pass through the epithelial cells that line the lumen wall before they can enter the hepatic portal circulation to be distributed systemically in blood circulation.
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